Complex B
Recent research & studies
- Research Progress on the Pathogenesis and Diagnostic and Therapeutic Potential of Ciliopathies Regulated by IFT172.
IFT172 is a core component of intraflagellar transport complex B (IFT-B), and pathogenic IFT172 variants disrupt ciliary transport, receptor localization, and tissue-specific signaling. This review summarizes evidence linking IFT172 dysfunction to neurological, retinal, skeletal, renal, and syndromic ciliopathy phenotypes, with…
- Topical Metformin Versus Triple Regimen for Epidermal Melasma
Melasma is a common skin condition that causes dark brown patches, mainly on sun-exposed areas of the face. It is often persistent, may recur after treatment, and can affect a person's quality of life. The standard topical triple regimen used…
- The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists
Background: Brown adipose tissue (BAT) is a type of fat in the body. It may prevent weight gain, improve insulin sensitivity, and reduce fatty liver. Researchers want to see if BAT helps the body burn energy. Objective: To learn more…
- Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color
The investigators aim to investigate the efficacy and tolerability of a hybrid non-ablative/ablative laser for acne scarring in skin of color.
- Metabolic Derangement and Vitamin Deficiencies.
Metabolic derangements and vitamin deficiencies represent one category of important, potentially reversible causes of acute encephalopathy, also termed "potentially reversible acute encephalopathic syndromes." This article summarizes their underlying pathophysiology and distinctive neuroimaging features, emphasizing disorders of glucose, ammonia, bilirubin, calcium-phosphorus…
- Unraveling emission narrowing pathways in N-embedded polyaromatic systems via sequential π-interlocking for efficient electroluminescence.
The growing demand for complex B-free, narrowband organic emitters has garnered significant attention for OLEDs, but preparing them remains challenging due to limited control over vibronic coupling and structural relaxation. Herein, we present a streamlined molecular design strategy based on…
- Microneedling-Assisted Metformin, Tranexamic Acid, and Modified Kligman's Formula for Melasma
Melasma is a common skin condition characterized by brown or gray patches on sun-exposed areas of the face. Although several topical treatments are available, treatment outcomes are often unsatisfactory, and recurrence is common. This randomized, parallel-group clinical trial aims to…
- Oral Tranexamic Acid Plus Triple Combination vs Triple Combination Alone in Melasma
The data will be collected after the permission of the ethical committee of hospital. Following the enrollment, patients will be selected by lottery in the two equal groups. Group A will be administered with oral tranexamic acid and triple combination…
- Heavy-chain immune repertoire sequencing enables language-model prediction of antigen-specific antibodies.
Rapidly identifying antigen-specific antibodies within complex B cell repertoires is important for therapeutic antibody discovery, vaccine development, disease surveillance, and immune condition monitoring, especially for emerging pandemics. RNA deep sequencing can rapidly provide antibody sequence candidates, but predicting their binding-specificity…
- From tissue to blood: an integrated multi-omics signature identifies fibrogenesis and neutrophil activation as key drivers of ulcerative colitis severity.
Introduction: Ulcerative colitis (UC) is an idiopathic chronic inflammatory disease of the colon characterized by severe disease burden and multiple co-morbidities. Currently, the endoscopic Mayo score is considered the gold standard for assessing disease severity in UC. However, the molecular…
These are third-party research studies presented for informational purposes. They are not endorsements and do not constitute medical advice or claims about any product.
