Kisspeptin
Recent research & studies
- Effects of vitamin D(3) on embryonic development, transcripts of genes encoding reproductive hormones, and its active metabolism in common carp (Cyprinus carpio L.).
Vitamin D3 (VD3) is a pleiotropic hormone with diverse physiological functions, but its role during early embryonic development in fish remains poorly understood. This study investigated the effects of aqueous VD3 exposure on embryonic survival, hatching, and the expression of…
- Seminal Plasma Kisspeptin-1 and Kisspeptin-54 Levels Are Associated With Semen Parameters and Oxidative Stress in Male Infertility.
Objective: Kisspeptin-1 and Kisspeptin-54 are key regulators of the hypothalamic-pituitary-gonadal axis and may play a role in male reproductive function. This study aimed to evaluate the association between seminal plasma kisspeptin levels and male infertility, and to examine their relationships…
- Stigmasterol alleviates central precocious puberty by targeting the IGF-1/PI3K/Akt/mTOR signaling pathway and modulating the Kisspeptin/GnRH axis.
Background: Central precocious puberty (CPP) results from premature activation of the hypothalamic-pituitary-gonadal axis, causing early sexual development and related health risks. Stigmasterol (ST), a natural phytosterol with diverse pharmacological activities, has not been fully evaluated for CPP. Methods: This study…
- Hyperkisspeptinemia and hypothalamic-pituitary-gonadal axis uncoupling in hemodialysis patients: clinical evidence suggestive of central desensitization.
Background: Reproductive and sexual dysfunction (uremic hypogonadism) are pervasive in maintenance hemodialysis (MHD) patients, yet the underlying neuroendocrine mechanisms remain poorly understood. Kisspeptin is the master upstream regulator of the hypothalamic-pituitary-gonadal (HPG) axis. We hypothesized that uremia-induced kisspeptin accumulation is…
- Daily Rhythmic Changes in Kisspeptin Gene Expression and Testosterone Hormone in Male Syrian Hamsters (Mesocricetus auratus).
This study examines how testosterone levels and kisspeptin gene expression are affected in male Syrian hamsters following pinealectomy and photoperiod modification. By examining the rhythmic changes in these parameters under long (16L: 8D) and short (8L: 16D) photoperiods, we aim…
- Kisspeptin Administration Subcutaneously to Patients With Hypothalamic Amenorrhea
The goal of this study is to see whether kisspeptin, a naturally occurring hormone, can stimulate the release of other reproductive hormones in women with hypothalamic amenorrhea (HA). The investigators are also examining whether kisspeptin can help women release eggs…
- The Molecular Basis of Inherited Reproductive Disorders
The goal of this study is to learn more about the genes that control puberty and reproduction in humans.
- Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease
The objective of this protocol is to use a case-control paradigm to compare the response to an intravenous administration of kisspeptin in individuals with and without post-covid-19 syndrome. The study subjects will receive a single bolus of kisspeptin.
- Kisspeptin Administration Subcutaneously to Patients With IHH
The goal of this study is to see whether kisspeptin, a naturally occurring hormone, can stimulate the release of other reproductive hormones in men and women with idiopathic hypogonadotropic hypogonadism (IHH). The investigators are also examining whether kisspeptin can help…
- Kissing as a Protective Factor Against Acidic pH in Saliva
The pH of saliva can be acidic or alkaline; When it is acidic, the tooth enamel is demineralized, that is, weakened. Additionally, bacteria in the mouth can increase and cause infections such as cavities. This occurs when we consume sugary…
These are third-party research studies presented for informational purposes. They are not endorsements and do not constitute medical advice or claims about any product.
