SS-31 is a premium-grade research peptide supplied in a lyophilized powder format and manufactured to stringent quality standards for laboratory and analytical research applications. Produced in a controlled manufacturing environment, each vial is formulated to ensure consistency, stability, and batch-to-batch uniformity. Every batch undergoes rigorous quality control procedures to verify product integrity and is intended exclusively for research and development purposes.
Recent research & studies
- Mitochondria-targeted MXene-based nanozymes promote mitophagy and inhibit mtDNA-triggered cGAS/STING inflammation in osteoarthritis.
Osteoarthritis (OA) is a prevalent and debilitating joint disease driven by progressive cartilage degradation, mitochondrial dysfunction, and chronic inflammation. In this study, we introduced MS@PMXene-TK, an innovative, mitochondria-targeted nanozyme designed for cartilage repair by addressing these key pathological features. This…
- Mitochondrial-targeted SS-31 peptide attenuates radiation-induced cardiomyocyte senescence.
Exposure to ionizing radiation, such as from radiation therapy or accidental radiation exposure can have adverse effects on the heart. While radiation injury in the heart may include cardiomyocyte senescence, there are no available strategies to prevent this phenomenon. This…
- Elamipretide: a mitochondria-targeting drug for Barth syndrome.
- Clinical Trial in Patients With Barth Syndrome- 4TAZPower
Phase 3b/4, randomized, double-blind, parallel-group, placebo-controlled clinical trial to evaluate the efficacy, safety, and pharmacokinetics of a once daily SC injection of elamipretide in subjects with genetically confirmed BTHS for 72 weeks. The primary trial objective is to confirm the…
- Mitochondrial-Targeted SS-31 Attenuates the Doxorubicin-Induced Cardiomyoblast H9C2 Cell Senescence.
Doxorubicin (DOX), an effective chemotherapeutic agent for many types of cancer, is known for significant cardiotoxic side effects, which largely limit its clinical usage. A 3 h treatment of cardiomyoblast H9C2 cells with a low concentration of DOX (100 nM)…
- The Role of Oxidative Stress in Heart Failure: Mechanisms and Therapeutic Targets.
Heart failure is characterised by increased production of reactive oxygen species (ROS), which contribute to apoptotic signalling. Changes in excitation-contraction coupling in heart failure promote increased calcium extrusion and decreased calcium uptake by myocardial mitochondria. Mitochondrial calcium is required to…
These are third-party research studies presented for informational purposes. They are not endorsements and do not constitute medical advice or claims about any product.
