SS-31 (10mg) Vial

Recent research & studies

• Seawater immersion reshapes the temporal dynamics of traumatic brain injury and reveals mitochondrial oxidative stress as a modifiable therapeutic target. — PubMed • Li W et al. • Exp Neurol • 2026 Aug 14

  Traumatic brain injury (TBI) evolves through time-dependent secondary injury, but whether seawater (SW) immersion merely amplifies pathology or reshapes the temporal trajectory of post-traumatic biology remains unclear. Here, we applied time-resolved proteomics to mouse brains after controlled cortical impact (CCI)…

• Chondrocyte membrane-camouflaged selenium nanoplatform with dual targeting for mitochondrial restoration and osteoarthritis therapy. — PubMed • Zhang Z et al. • J Control Release • 2026 Aug 12

  Precise mitochondrial targeting in chondrocytes is essential for interrupting the vicious cycle of oxidative stress and cartilage degeneration in osteoarthritis (OA). Here, we develop a biomimetic nanoplatform (CM@SS31-Se) with dual targeting capability. This system comprises selenium nanoparticles with glutathione peroxidase…

• Targeting Mitochondria for Postoperative Cognitive Dysfunction: From Mechanisms to Therapeutics. — PubMed • Zhang A et al. • Mol Neurobiol • 2026 Aug 8

  Postoperative cognitive dysfunction (POCD) is a frequent neurological complication in older surgical patients, leading to substantial declines in quality of life and placing a considerable burden on society. This review provides a comprehensive overview of how mitochondrial dysfunction contributes to…

• Disruption of hippocampal mitochondrial function underlies opioid-induced postoperative cognitive dysfunction in aged rats. — PubMed • Muscat SM et al. • Brain Behav Immun • 2026 Aug 3

  Postoperative cognitive dysfunction (POCD) is a common and persistent complication in aging individuals following surgery, particularly when opioids are used for perioperative pain management. Although opioids are widely administered in the perioperative setting, the mechanisms by which they contribute to…

• Clinical Trial in Patients With Barth Syndrome- 4TAZPower — ClinicalTrials.gov • Recruiting • Phase4 • July 13, 2026

  Phase 3b/4, randomized, double-blind, parallel-group, placebo-controlled clinical trial to evaluate the efficacy, safety, and pharmacokinetics of a once daily SC injection of elamipretide in subjects with genetically confirmed BTHS for 72 weeks. The primary trial objective is to confirm the…

• The Role of Oxidative Stress in Heart Failure: Mechanisms and Therapeutic Targets. — PubMed • Hussain T et al. • Cureus • 2026 Jun

  Heart failure is characterised by increased production of reactive oxygen species (ROS), which contribute to apoptotic signalling. Changes in excitation-contraction coupling in heart failure promote increased calcium extrusion and decreased calcium uptake by myocardial mitochondria. Mitochondrial calcium is required to…

These are third-party research studies presented for informational purposes. They are not endorsements and do not constitute medical advice or claims about any product.