Glutathione
Recent research & studies
- Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer
This phase III trial compares the effect of adding cemiplimab to standard therapy (surgery with or without radiation) versus standard therapy alone in treating patients with stage III/IV squamous cell skin cancer that is able to be removed by surgery…
- Vitamin E Add-On Therapy, Thyroid Function & Oxidative Stress in Levothyroxine-Treated Hypothyroidism
The aim of this study is to learn if vitamin E supplementation as an adjunct to levothyroxine therapy help to reduce oxidative stress, improve antioxidant defence mechanisms, and favourably influence thyroid hormone status, making it a promising therapeutic strategy for…
- Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
This phase III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin Hylecta [TM]) or pertuzumab, trastuzumab and hyaluronidase-zzxf (Phesgo [TM]) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial cancer. Trastuzumab and…
- A Cascaded DNA Nanocircuit for Multi-Signal-Responsive Precision siRNA Delivery in Cancer Therapy.
Precision control over nucleic acid delivery remains a critical challenge in cancer therapy, particularly for siRNA-based gene silencing, where off-target effects limit clinical translation. Herein, we report a programmably engineered DNA nanocircuit with cascaded dual-AND logic gates, which enables the…
- Monochromatic green and blue light stimulated fat production in the liver and abdominal fat tissue of broilers.
1. This study evaluated the effects of monochromatic lights on lipid metabolism, inflammation and antioxidant capacity in broilers. Eighty newly hatched broilers were assigned to four treatment groups (n = 20/group) and exposed to white (400-700 nm), red (660 nm), green (560 nm), or blue…
- NRP + ex Situ HMPO2 vs NRP Alone in DCD Kidney Transplantation
The goal of this clinical trial is to learn if the combination of Normothermic Regional Perfusion (NRP) at the time of organ procurement with ex situ Hypothermic Oxygenated Perfusion (HMPO2) of kidneys recovered from donors after circulatory death (DCD) is…
- Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer
This phase III trial compares standard therapy given after surgery (adjuvant) to standard therapy given before and after surgery (perioperative) in treating patients with stage II-IIIB non-small cell lung cancer (NSCLC) that can be removed by surgery (resectable). The usual…
- Effect of Treadmill Training on Ovarian Alterations in A Rat Model of Congenital Hypothyroidism.
Objective: Thyroid hormones are essential for fetal development, and maternal hypothyroidism may cause reproductive abnormalities in offspring. Physical activity may provide therapeutic benefits. This study investigated the effects of treadmill training on gonadotropin levels, oxidative stress biomarkers, and ovarian histopathological…
- Prunetin Attenuates Dexamethasone-Induced Pancreatic β-Cell Apoptosis: Modulation of Oxidative Stress and MAPK Signaling but Not Phosphorylated C-Abl Levels.
Dexamethasone has been reported to induce pancreatic β-cell apoptosis, which may contribute to steroid-induced diabetes following long-term glucocorticoid therapy. Although prunetin, a natural isoflavone, has been shown to attenuate dexamethasone-induced pancreatic β-cell apoptosis with suppression of p53 signaling as an…
- Evaluation of Oxidative Stress and Its Impact on Sperm DNA Fragmentation and Semen Parameters in Infertile Men.
Oxidative stress, defined as an imbalance between reactive oxygen species (ROS) production and antioxidant defenses, plays a central role in the pathophysiology of male infertility and has been reported in approximately 30%-80% of infertile men. Excessive ROS production promotes lipid…
These are third-party research studies presented for informational purposes. They are not endorsements and do not constitute medical advice or claims about any product.
